Pumpkin seed oil (prostafit) or prazosin? Which one is better in the treatment of symptomatic benign prostatic hyperplasia.

Shirvan, Maliheh Keshvari and Mahboob, Mohammad Reza Darabi and Masuminia, Mehdi and Mohammadi, Shabnam (2014) Pumpkin seed oil (prostafit) or prazosin? Which one is better in the treatment of symptomatic benign prostatic hyperplasia. JPMA. The Journal of the Pakistan Medical Association, 64 (6). pp. 683-5. ISSN 0030-9982

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Abstract

OBJECTIVE To assess the efficacy of drugs containing herbal extracts in the treatment of Benign Prostatic Hyperplasia. METHODS The clinical trial study was performed in 2011-2012 at Imam Reza Hospital, Mashhad, Iran. One hundred patients with Benign Prostatic Hyperplasia were randomly divided into 2 equal groups receiving prostafit and prazosin, respectively. Quality of life and International Prostatic Symptom Score questionnaire were filled and prostate specific antigen level, uroflowmetry and prostate volume were measured at baseline, 3 and 6 months after the medication. The data was analysed using SPSS 15 and repeated measure analysis of variance. RESULTS No complications were observed during and after the treatment. International Prostatic Symptom Score had significant differences at baseline and 6 months after the treatment in both groups, specially in group 2 18 vs 22 (36% versus 44%). Quality of life was better in group 2, 25.5 vs 31.5 (51% versus 63%). prostate specific antigen level did not change after the treatment and there was no remarkable difference in either group. CONCLUSION Prostafit is an effective and safe treatment in Benign Prostatic Hyperplasia but not as much as prozasin.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
Depositing User: Unnamed user with email eprints@gmu.ac.ir
Date Deposited: 04 Mar 2017 08:19
Last Modified: 04 Mar 2017 08:19
URI: http://eprints.gmu.ac.ir/id/eprint/101

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