Determining the Efficacy of Some Hospital Disinfectants on Methicillin-Resistant Staphylococci Isolated from Different Wards of an Educational Hospital

Sajjadi, Seyed Ali and Mardaneh, Jalal and Mohammadzadeh, Alireza and Hojjatpanah, Roghye and Amiri, Mostafa and Ghasemi, Mehdi Determining the Efficacy of Some Hospital Disinfectants on Methicillin-Resistant Staphylococci Isolated from Different Wards of an Educational Hospital. Crescent Journal of Medical and Biological Sciences, 7 (1).

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Abstract

Objectives: Methicillin-resistant staphylococci are important causes of nosocomial infections. Due to the presence of these bacteria in hospitals as a significant challenge in hospital infection control, the identification of effective disinfectants against methicillin-resistant staphylococci is necessary. This study was designed to evaluate the effectiveness of common hospital disinfectants against methicillin-resistant staphylococci. Materials and Methods: In this cross-sectional study, the effectiveness of 4 surface disinfectant cleaners (Deconex 50 AF, Microzed GP-H, Peranacid M1 and Surfocept quick) against methicillin-resistant staphylococci (10 Staphylococcus aureus, 10 Staphylococcus saprophyticus, and 55 Staphylococcus epidermidis) was evaluated using broth dilution method, disc diffusion assay, and cell viability assay. Results: The minimum inhibitory concentrations (MICs) and minimum bactericidal concentrations (MBCs) of Peranacid and Surfocept against the isolates were higher than those of Deconex and Microzed. The results of disk diffusion assay showed that staphylococcus strains exhibited greater inhibition zone diameter than other disinfectants at different concentrations of Deconex and Microzed. According to the results of cell viability assay, S. aureus, S. epidermidis, and S. saprophyticus isolates did not grow at three concentrations (0.5%, 1% and 2%) of Deconex, Microzed, and Peranacid, respectively. Conclusions: Deconex and Microzed had more antimicrobial properties than the 2 other agents and methicillin-resistant staphylococcus isolates had a higher resistance to both Peranacid and Surfosept.

Item Type: Article
Subjects: R Medicine > R Medicine (General)
R Medicine > RZ Other systems of medicine
Depositing User: Unnamed user with email eprints@gmu.ac.ir
Date Deposited: 28 Sep 2020 05:38
Last Modified: 28 Sep 2020 05:38
URI: http://eprints.gmu.ac.ir/id/eprint/1900

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