miRNA-based strategy for modulation of influenza A virus infection

Keshavarz, Mohsen and Dianat-Moghadam, Hassan and Sofiani, Vahideh Hamidi and Karimzadeh, Mohammad and Zargar, Mohsen and Moghoofei, Mohsen and Biglari, Hamed and Ghorbani, Saied and Nahand, Javid Sadri and Mirzaei, Hamed miRNA-based strategy for modulation of influenza A virus infection. Epigenomics. null.

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Official URL: https://doi.org/10.2217/epi-2017-0170

Abstract

Influenza A virus is known worldwide as a threat associated with human and livestock diseases. Hence, identification of physiological and molecular aspects of influenza A could contribute to better design of therapeutic approaches for reducing adverse effects associated with disease caused by this virus. miRNAs are epigenetic regulators playing important roles in many pathological processes that help in progression of influenza A. Besides miRNAs, exosomes have ememrged as other effective players in influenza A pathogenesis. Exosomes exert their effects via targeting their cargos (e.g., DNAs, mRNA, miRNAs and proteins) to recipient cells. Here, we summarized various roles of miRNAs and exosomes in influenza A pathogenesis. Moreover, we highlighted therapeutic applications of miRNAs and exosomes in influenza.

Item Type: Article
Additional Information: PMID: 29888954
Subjects: R Medicine > R Medicine (General)
R Medicine > RA Public aspects of medicine
R Medicine > RZ Other systems of medicine
Depositing User: Unnamed user with email eprints@gmu.ac.ir
Date Deposited: 03 Jul 2018 10:07
Last Modified: 03 Jul 2018 10:07
URI: http://eprints.gmu.ac.ir/id/eprint/407

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