Two dimension (2-D) graphene-based nanomaterials as signal amplification elements in electrochemical microfluidic immune-devices: Recent advances

Hasanzadeh, Mohammad and Shadjou, Nasrin and Mokhtarzadeh, Ahad and Ramezani, Mohammad (2016) Two dimension (2-D) graphene-based nanomaterials as signal amplification elements in electrochemical microfluidic immune-devices: Recent advances. Materials Science and Engineering: C, 68. 482 - 493.

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Abstract

Abstract Graphene is a 2-D carbon nanomaterial with many distinctive properties that are electrochemically beneficial, such as large surface-to-volume ratio, lowered power usage, high conductivity and electron mobility. Graphene-based electrochemical immune-devices have recently gained much importance for detecting antigens and biomarkers responsible for cancer diagnosis. This review describes fabrication and chemical modification of the surfaces of graphene for immunesensing applications. We also present a comprehensive overview of current developments and key issues in the determination of some biological molecules with particular emphasis on evaluating the models. This review focuses mostly on new developments in the last 5 years in development of chip architecture and integration, different sensing modes that can be used in conjunction with microfluidics, and new applications that have emerged or have been demonstrated; it also aims to point out where future research can be directed to in these areas.

Item Type: Article
Uncontrolled Keywords: Bioelectronics
Subjects: R Medicine > R Medicine (General)
R Medicine > RZ Other systems of medicine
Depositing User: Unnamed user with email eprints@gmu.ac.ir
Date Deposited: 28 Feb 2017 06:04
Last Modified: 28 Feb 2017 06:04
URI: http://eprints.gmu.ac.ir/id/eprint/50

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